FlashcardsAntifungal Drugs Flashcards
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This 30-card flashcard set covers antifungal pharmacology including Amphotericin B, azoles, echinocandins, griseofulvin, and terbinafine. Cards address mechanisms of action, adverse effects, drug resistance, and clinical applications. Designed for healthcare students and professionals studying antifungal therapy, infection control, or preparing for board exams.
Terms in This Set
- What are the two forms of fungi?
- Why is it more difficult to develop selective antifungal agents compared to antibacterial agents?
- What are superficial fungal infections? Give an example.
- What are invasive fungal infections? Give examples.
- What factors have contributed to the increase in invasive fungal infections?
- Name a class of antifungal agents that inhibit fungal membrane stability.
- What is the mechanism of action of Amphotericin B?
- What are the common adverse effects of Amphotericin B?
- What is Nystatin used for?
- What is the mechanism of action of Flucytosine?
- What are the adverse effects of Flucytosine?
- What is Terbinafine and its mechanism of action?
- What are the common adverse effects of Terbinafine?
- What are the major azole antifungal agents?
- What is the mechanism of action of azoles?
- What is a common resistance mechanism to azoles?
- What are the adverse effects of Fluconazole?
- What is the significance of Voriconazole?
- What is the mechanism of action of Echinocandins?
- What are the common agents in the Echinocandin class?
- What is Griseofulvin and its mechanism of action?
- What are the common adverse effects of Griseofulvin?
- How is Amphotericin B administered?
- What formulation of Amphotericin B is less nephrotoxic?
- What is the role of squalene epoxidase in fungal cells?
- What is the significance of renal excretion in the pharmacokinetics of Fluconazole?
- What is the boxed warning associated with Flucytosine?
- What is the effect of concurrent therapy with nephrotoxic agents on Amphotericin B?
- What is the effect of Terbinafine on mammalian cells?
- What is the primary route of administration for Echinocandins?
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